Therapies
Ozone Therapy
Prolozone injections, IV ozone, and systemic ozone protocols at Progressive Medical Center in Atlanta. Medical-grade oxygen therapy that delivers targeted healing for chronic pain, infection, and inflammation, working with your body's own capacity to recover.
Medical-Grade Oxygen Therapy
What Is Ozone Therapy?
You are dealing with pain that has not responded to conventional treatment, or a chronic condition that keeps cycling without resolution. Standard approaches may have managed symptoms for a while, but the underlying problem remains. Your body has the ability to heal. Sometimes it needs the right biological signal to get the process moving again.
Ozone therapy uses medical-grade ozone, a molecule made up of three oxygen atoms (O3), to stimulate your body's natural repair and immune pathways. When ozone is introduced into the body, it converts to regular oxygen and a cascade of biological responses follows: increased blood flow, enhanced oxygen delivery, immune activation, and reduced inflammation. The result is targeted healing in areas where the body has been struggling to recover on its own.
At Progressive Medical Center in Atlanta, we use multiple forms of ozone therapy depending on your condition and treatment goals. From prolozone joint injections to intravenous protocols, ozone is one of the most versatile tools in our integrative approach to complex and chronic cases.
How It Works
Ozone Delivered Where Your Body Needs It
Ozone therapy works by introducing a concentrated form of oxygen that triggers a controlled biological response. Once in the body, ozone converts to regular oxygen (O2) and activates fibroblasts and chondroblasts, the cells responsible for producing collagen and cartilage. It improves local blood flow, enhances oxygen and nutrient delivery, and supports the immune system's ability to fight infection and clear inflammation.
At PMC, our providers select the ozone protocol that matches your clinical picture. For localized pain and joint conditions, prolozone injections deliver ozone directly to the affected area. For systemic conditions, intravenous ozone therapies circulate ozone through the bloodstream for whole-body impact. Your diagnostic results and treatment goals determine which approach, or combination of approaches, is right for you.
Treatment Options
Ozone Therapies We Offer
Progressive Medical Center offers multiple forms of ozone therapy. Your provider determines which approach fits your condition and treatment plan.
Prolozone Injections
Prolozone therapy involves injecting a combination of medical-grade ozone and essential nutrients directly into and around damaged joints, ligaments, and soft tissue. The injection delivers oxygen and healing compounds precisely where they are needed, stimulating tissue repair and strengthening damaged structures. Prolozone is a non-surgical approach to chronic musculoskeletal pain that targets the root cause rather than masking symptoms.
Best for: Joint pain, back and neck pain, rotator cuff injuries, degenerative disc disease, arthritis, sports injuries
IV Ozone Therapy (MAH)
Major autohemotherapy (MAH) is a form of intravenous ozone therapy where a small volume of blood is drawn, infused with medical-grade ozone, and returned to the body. This systemic approach exposes the blood to therapeutic ozone concentrations, activating immune responses, improving oxygen utilization at the cellular level, and supporting the body's ability to fight chronic infections and reduce systemic inflammation.
Best for: Chronic infections, immune dysfunction, fatigue, inflammatory conditions, general wellness optimization
Ten-Pass Ozone Therapy
Ten-pass ozone therapy is a high-dose protocol that repeats the blood-ozone-reinfusion cycle ten times in a single session. This delivers a significantly higher concentration of ozone than standard MAH, allowing for deeper systemic effects. The process uses a closed-loop system under controlled pressure, making it one of the most potent ozone protocols available. Ten-pass is reserved for patients who need aggressive immune and detoxification support.
Best for: Complex chronic illness, autoimmune conditions, Lyme disease, severe fatigue, patients who have plateaued on standard protocols
Looking for full-body blood ozonation? PMC also offers EBOO therapy, our most advanced ozone-based protocol, which filters and treats up to 2 liters of blood through a closed-loop system.
Why Ozone Therapy
What Ozone Therapy Can Do
By delivering oxygen in a biologically active form, ozone therapy supports multiple healing pathways throughout the body.
Pain Relief and Joint Repair
Prolozone injections deliver oxygen and nutrients directly to damaged joints and ligaments, stimulating the production of collagen and cartilage. This strengthens and stabilizes injured tissue, reducing pain at its source rather than masking it with medication. Patients with chronic back pain, knee arthritis, and rotator cuff injuries often experience significant improvement.
Reduced Inflammation
Chronic inflammation drives many of the conditions PMC treats. Ozone therapy helps regulate the inflammatory response by improving oxygen delivery to inflamed tissues and activating anti-inflammatory pathways. For patients stuck in cycles of pain and swelling that conventional treatment has not resolved, ozone can help break the pattern.
Immune System Activation
Ozone modulates the immune system, helping it respond more effectively to chronic infections, bacterial overgrowth, and viral persistence. At therapeutic concentrations, ozone enhances white blood cell activity and supports the body's ability to identify and clear pathogens. This makes IV ozone and ten-pass protocols particularly valuable for patients with persistent infections.
Improved Circulation and Oxygenation
Ozone improves the flexibility and efficiency of red blood cells, enhancing their ability to carry and deliver oxygen throughout the body. Better circulation means tissues that have been starved of oxygen, particularly in areas with compromised blood flow, begin receiving the resources they need to heal and function.
Tissue Regeneration
By activating fibroblasts and chondroblasts, ozone therapy stimulates the production of new collagen, cartilage, and connective tissue. This regenerative effect is why prolozone injections can address structural damage that other non-surgical approaches cannot. The body rebuilds and stabilizes the damaged area rather than just reducing symptoms.
Detoxification Support
Ozone helps the body break down and eliminate toxic compounds, metabolic waste, and damaged cells. For patients dealing with environmental toxin exposure, mold illness, or the cumulative burden of chronic disease, ozone therapy supports the body's detoxification pathways at the cellular level. Combined with other PMC therapies, the detox effect is amplified.
Who Can Benefit
Conditions That Respond to Ozone Therapy
Because ozone therapy can be delivered both locally and systemically, the range of conditions it addresses spans musculoskeletal pain, chronic illness, and immune dysfunction.
Not sure which ozone therapy is right for your situation? Call (770) 676-6000 and our care team will help you find the right starting point.
Your Ozone Therapy Experience
What to Expect
From your initial consultation through your treatment sessions, here is what the process looks like at Progressive Medical Center.
Consultation and Evaluation
Your provider reviews your health history, current symptoms, and diagnostic results to determine which ozone protocol is appropriate. For joint and musculoskeletal conditions, the evaluation focuses on the specific area of pain and structural damage. For systemic conditions, your doctor evaluates how ozone fits into your broader treatment plan alongside diagnostics and other therapies. The consultation covers your full clinical picture.
Treatment Selection
Based on your evaluation, your provider recommends the ozone protocol that matches your needs. Prolozone injections target specific joints, ligaments, or soft tissue areas. IV ozone and ten-pass therapy address systemic conditions through the bloodstream. Some patients benefit from a combination of both targeted and systemic approaches. Your care team explains the recommended protocol, expected timeline, and what to prepare for before your first session.
The Treatment Session
For prolozone injections, your provider administers the ozone and nutrient combination directly to the treatment area. The procedure is quick, typically completed in 15 to 30 minutes. Some soreness at the injection site is common for 1 to 3 days afterward, a normal part of the healing response. For IV ozone and ten-pass therapy, you sit comfortably while the treatment is administered through an IV line over 30 to 90 minutes depending on the protocol. Most patients relax during the session.
Ongoing Care and Progress Tracking
Prolozone sessions are typically repeated every 1 to 2 weeks until maximum improvement is reached. IV ozone frequency depends on your condition and response. Your provider tracks how you are responding after each session and adjusts the protocol accordingly. Many patients experience significant improvement within a few treatments. Others with long-standing conditions may require a longer series. Lab work and functional diagnostics help measure your progress objectively over time.
The Difference
Standalone Ozone Clinics vs. Ozone at PMC
Many clinics offer ozone therapy as an isolated service. At Progressive Medical Center, ozone is one part of a comprehensive treatment strategy guided by advanced diagnostics and a coordinated care team.
Standalone Ozone Clinics
- Ozone offered as a single standalone treatment
- Limited or no diagnostic testing to guide protocols
- One ozone modality available (typically MAH only)
- No coordinated treatment plan across therapies
- Results dependent on ozone alone
- Generic protocols without individualization
Ozone Therapy at PMC
- Ozone integrated into a full treatment strategy
- Advanced diagnostics guide which ozone protocol you receive
- Multiple ozone modalities (prolozone, MAH, ten-pass)
- Coordinated with IV therapy, EBOO, HBOT, and other treatments
- Each therapy amplifies the others for compounding results
- Individualized protocols based on your labs and clinical picture
Common Questions
Ozone Therapy FAQ
Is ozone therapy safe?
Yes. Ozone therapy has been used in clinical settings for decades. At PMC, all ozone treatments are administered by trained medical professionals using medical-grade ozone generators and sterile protocols. Side effects are uncommon. For prolozone injections, some soreness at the injection site for 1 to 3 days is normal and expected. For IV and ten-pass ozone, mild fatigue or a brief detox response may occur as the body processes the treatment.
Does prolozone therapy hurt?
Most patients describe prolozone injections as tolerable with brief discomfort during the injection. Some patients feel pressure as the ozone and nutrient solution is delivered. Any discomfort during the procedure is short-lived, and the soreness that follows over the next 1 to 3 days is a normal part of the healing response. Many patients report that the mild soreness is a welcome trade for the pain relief that follows. Your provider can discuss comfort measures if you have concerns about sensitivity.
How many ozone sessions will I need?
That depends on your condition, its severity, and how your body responds. For prolozone injections, sessions are typically repeated every 1 to 2 weeks until maximum improvement is reached. Some patients experience significant relief within 3 to 4 treatments. Others with long-standing conditions may need a longer series. For IV ozone and ten-pass therapy, frequency is determined by your overall treatment plan and clinical response. Your provider tracks your progress and adjusts accordingly.
How is prolozone different from cortisone injections?
Cortisone reduces inflammation temporarily but does not promote tissue repair. The pain relief often fades, and repeated cortisone injections can actually weaken joint structures over time. Prolozone takes the opposite approach: it stimulates the body's own repair mechanisms by increasing oxygen and nutrient delivery to the damaged area, promoting the production of new collagen and cartilage. The goal is structural repair, not just symptom suppression.
How much does ozone therapy cost?
Ozone therapy costs are discussed during your initial consultation. Your provider explains the recommended treatment protocol and associated costs before any sessions begin. PMC is out-of-network, but we provide superbills for insurance reimbursement. Cherry Financing and CareCredit are also available. Visit our Insurance and Financing page for details.
Do you accept insurance for ozone therapy?
PMC is an out-of-network provider. We provide superbills (detailed receipts) that you can submit to your insurance company for potential reimbursement. Some ozone therapy sessions may qualify for coverage depending on your plan and diagnosis. Our team can help you understand your options. Visit our Insurance and Financing page for more information.
What is the difference between ozone therapy and EBOO?
Both use ozone, but they work differently. Standard ozone therapy (MAH and prolozone) treats either a specific area or a small volume of blood. EBOO (Extracorporeal Blood Oxygenation and Ozonation) treats up to 2 liters of blood through a continuous closed-loop system that also includes built-in filtration. EBOO provides deeper systemic detoxification and is typically reserved for complex cases. Your provider can help determine which ozone approach, or combination, is right for your situation. Learn more on our EBOO Therapy page.
I am traveling from out of town. Can I receive ozone therapy during my visit?
Absolutely. PMC regularly treats out-of-town patients and can coordinate ozone therapy sessions into your visit schedule alongside other treatments. Your patient navigator plans your itinerary so diagnostic testing, consultations, and therapies happen efficiently during your stay. Visit our Out-of-Town Patients page for details on how we support traveling patients.
Ready to Explore Ozone Therapy?
Schedule a consultation with our team to find out which ozone protocol is the right fit for your condition and treatment goals. No referral needed.